Health-promoting and therapeutic attributes of milk-derived bioactive peptides
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Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Nutrients
Abstract
Milk-derived bioactive peptides (BAPs) possess several potential attributes in terms of
therapeutic capacity and their nutritional value. BAPs from milk proteins can be liberated by bacterial
fermentation, in vitro enzymatic hydrolysis, food processing, and gastrointestinal digestion. Previous
evidence suggested that milk protein-derived BAPs have numerous health-beneficial characteristics,
including anti-cancerous activity, anti-microbial activity, anti-oxidative, anti-hypertensive, lipidlowering,
anti-diabetic, and anti-osteogenic. In this literature overview, we briefly discussed the
production of milk protein-derived BAPs and their mechanisms of action. Milk protein-derived
BAPs are gaining much interest worldwide due to their immense potential as health-promoting
agents. These BAPs are now used to formulate products sold in the market, which reflects their
safety as natural compounds. However, enhanced commercialization of milk protein-derived BAPs
depends on knowledge of their particular functions/attributes and safety confirmation using human
intervention trials. We have summarized the therapeutic potentials of these BAPs based on data from
in vivo and in vitro studies.
Description
Keywords
milk proteins; bioactive peptides; anti-inflammation; anti-diabetic; anti-hypertensive; therapeutic potentials