Recent Trends in the Design, Synthesis and Biomedical Applications of Covalent Organic Frameworks
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Date
2022-12
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Abstract
The most recent and advanced class of crystalline and permeable compounds are covalent
organic frameworks (COFs). Due to their exceptional qualities, such as their porous structure, high
surface area, strong chemical and thermal stabilities, low density, good water stability, luminescent
nature, and so on, COFs have seen remarkable growth over the past ten years. COFs have been
successfully researched for a number of applications based on these characteristics. The current state
of COFs has been reported in this study, with particular attention paid to their design, topology,
synthesis, and a variety of biological applications, including drug delivery systems, photodynamic
and photothermal therapy, biosensing, bioimaging, etc. Moreover, several miscellaneous applications,
such as catalysis, gas storage and separation, photocatalysis, sensors, solar cells, supercapacitors, and
Citation: Kaur, G.; Kumar, D.;
Sundarrajan, S.; Ramakrishna, S.;
Kumar, P. Recent Trends in the
Design, Synthesis and Biomedical
Applications of Covalent Organic
Frameworks. Polymers 2023, 15, 139.
https://doi.org/10.3390/
polym15010139
Academic Editors: Yadong Tang and
Lu Jiang
Received: 12 November 2022
Revised: 20 December 2022
Accepted: 21 December 2022
Published: 28 December 2022
Copyright: © 2022 by the authors.
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://
creativecommons.org/licenses/by/
4.0/).
3D printers, have also been explored. It is significant that we have examined current research on
COFs with a focus on the biological applications, which are infrequently covered in the literature.
Descriptions of the difficulties and prospective outcomes have also been given.