2-Deoxy-D-Glucose: A Novel Pharmacological Agent for Killing Hypoxic Tumor Cells, Oxygen Dependence-Lowering in Covid-19, and Other Pharmacological Activities

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dc.contributor.authorSingh, R
dc.contributor.authorGupta, V
dc.contributor.authorKumar, A
dc.contributor.authorSingh, K
dc.date.accessioned2024-10-14T05:30:01Z
dc.date.available2024-10-14T05:30:01Z
dc.date.issued2023-03
dc.description.abstractTe nonmetabolizable glucose analog 2-deoxy-D-glucose (2-DG) has shown promising pharmacological activities, including inhibition of cancerous cell growth and N-glycosylation. It has been used as a glycolysis inhibitor and as a potential energy restriction mimetic agent, inhibiting pathogen-associated molecular patterns. Radioisotope derivatives of 2-DG have applications as tracers. Recently, 2-DG has been used as an anti-COVID-19 drug to lower the need for supplemental oxygen. In the present review, various pharmaceutical properties of 2-DG are discussed.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/1626
dc.title2-Deoxy-D-Glucose: A Novel Pharmacological Agent for Killing Hypoxic Tumor Cells, Oxygen Dependence-Lowering in Covid-19, and Other Pharmacological Activitiesen_US
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