Integrated network pharmacology and in-silico approaches to decipher the pharmacological mechanism of Selaginella tamariscina in the treatment of non-small cell lung cancer
Loading...
Date
2023-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Non-small cell lung cancer (NSCLC) is a major pathological type of lung cancer and accounts for more than
80% of all cases. In healthcare management, it is challenging to understand the mechanism of NSCLC due to
diverse spectra and the limited number of reported data. Selaginella tamariscina is an evergreen perennial
plant, hermaphrodite, and used to treat numerous diseases, including NSCLC. In vitro research revealed the
therapeutic importance of S. tamariscina in contrast to NSCLC, but the molecular mechanism is still unclear.
In the present study, a network pharmacology technique was employed to uncover the active ingredients, their
potential targets, and signaling pathways in S. tamariscina for the treatment of NSCLC.