A Gene Expression Atlas of the Domestic Water Buffalo (Bubalus bubalis)
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Date
2019-07
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Abstract
The domestic water buffalo (Bubalus bubalis) makes a major contribution to the global
agricultural economy in the form of milk, meat, hides, and draught power. The global
water buffalo population is predominantly found in Asia, and per head of population
more people depend upon the buffalo than on any other livestock species. Despite
its agricultural importance, there are comparatively fewer genomic and transcriptomic
resources available for buffalo than for other livestock species. We have generated a
large-scale gene expression atlas covering multiple tissue and cell types from all major
organ systems collected from three breeds of riverine water buffalo (Mediterranean,
Pandharpuri and Bhadawari) and used the network analysis tool Graphia Professional
to identify clusters of genes with similar expression profiles. Alongside similar data, we
and others have generated for ruminants as part of the Functional Annotation of Animal
Genomes Consortium; this comprehensive transcriptome supports functional annotation
and comparative analysis of the water buffalo genome.