Browsing by Author "Rana, A"

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    Anti-fertility and abortifacient activity of hydroalcoholic fruit pulp extract of Tamarindus indica
    (2023-11) Kaur, M; Rana, A; Kumar, S; Kumari, B
    ABSTRACT Background: Medicinal plants have been widely used for treatment and management of various diseases. There are many different types of commercialized synthetic contraceptives on the market today for controlling fertility, these cannot be utilized since they have serious side effects such weight gain, hormonal alterations, hyperten sion, and cancer . In India, indigenous women from Tripura & Maharashtra have historically utilized the fruit pulp of Tamarindus Indicus to induce abortion. However, there is currently no accessible scientific data sup porting the use of this plant for fertility control. Methods: The current study’s objective was to evaluate the hydroalcoholic extract of Tamarindus indica fruit pulp’s ability to induce abortion in female Wistar rats. In this experimental animal model, contraceptive activity of hydroalcoholic extract of Tamarindus indica (HAETI) was evaluated for anti-implantation, abortifacient, and estrogenic/antiestrogenic action. Female rats having ovariectomies were given HAETI extract (500 mg/kg) for 7 straight days to test to evaluate the estrogenic/anti-estrogenic action. All animals were killed on the eighth day, and the blood serum was then processed to determine the levels of several hormones, including LH, FSH, pro lactin, estrogen, and others, as well as biochemical markers including cholesterol, total protein, glycogen, and alkaline phosphates. In this model, modifications to uterine histoarchitecture were also investigated. The extract was administered from the 1 to7 day of pregnancy. On 10th day, laparotomy was performed to evaluate the no. of implants in female rats. Results: Steroids, flavonoids, saponins, tannins, and alkaloids were detected during phytochemical analysis of the extract. the HAETI extract demonstrated significant anti-implantation and abortifacient effects. Additionally, the extract demonstrated significant estrogenic activity as evident by uterine histological parameters including in creases in endometrium thickness and height, vaginal cornification. Further, the study found marked increases in glycogen, alkaline phosphate, estrogen, cholesterol levels when given alone or in combination with estradiol valerate. LH, FSH, and a little increase in prolactin levels were suppressed after HAETI administration. Conclusions: Our study’s findings showed that Tamarindus indica fruit pulp hydroalcoholic extract has a potent contraceptive effect, which may be explained by the phytoconstituents of the plant’s capacity to inhibit im plantation and have an estrogenic effect. Further investigation on Tamarindus indica as a potential natural anti implantation agent allow for new abortive drug.
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    Enhance traffic flow prediction with Real-Time Vehicle Data Integration
    (2023-08) Jain, R; Dhingra, S; Joshi, K; Rana, A; Goyal, N
    This study examines how sophisticated traffic control systems affect traffic flow. These cutting-edge solutions use real-time traffic data to increase road networks’ intelligence. These technologies enable the creation of a smoother and more efficient traffic flow by enhancing traffic signal timings and automatically rerouting cars towards less crowded routes. Notably, these innovations significantly lower air pollution, greenhouse gas emissions, and fuel consumption while also minimizing the financial and time expenses related to traffic congestion. Our unique Real-Time Vehicle Data Integration (RTVDI) algorithm is being used to portray the potential of intelligent traffic control systems. These technologies have the potential to revolutionize traffic management procedures by using real-time data and complex processes. They have the potential to improve commuter safety, increase road efficiency, and improve traffic flow.
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    Enhance traffic flow prediction with Real-Time Vehicle Data Integration
    (2023-08) Jain, R; Dhingra, S; Joshi, K; Rana, A; Goyal, N
    This study examines how sophisticated traffic control systems affect traffic flow. These cutting-edge solutions use real-time traffic data to increase road networks’ intelligence. These technologies enable the creation of a smoother and more efficient traffic flow by enhancing traffic signal timings and automatically rerouting cars towards less crowded routes. Notably, these innovations significantly lower air pollution, greenhouse gas emissions, and fuel consumption while also minimizing the financial and time expenses related to traffic congestion. Our unique Real-Time Vehicle Data Integration (RTVDI) algorithm is being used to portray the potential of intelligent traffic control systems. These technologies have the potential to revolutionize traffic management procedures by using real-time data and complex processes. They have the potential to improve commuter safety, increase road efficiency, and improve traffic flow.
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    Exploring prebiotic properties and its probiotic potential of new formulations of soy milk-derived beverages
    (2024-07) Rana, A; Taneja, N; Raposo, A; Alarifi, S; Lemos, E; Dhewa, T
    Introduction: The food and beverage industry has shown a growing interest in plant based beverages as alternatives to traditional milk consumption. Soy milk is derived from soy beans and contains proteins, isoflavones, soy bean oligosaccharides, and saponins, among other ingredients. Because of its high nutritive value and versatility, soy milk has gained a lot of attention as a functional food. Methods: The present work aims to explore the prebiotic properties and gastrointestinal tolerance potential of new formulations of soy milk-derived drinks to be fermented with riboflavin-producing probiotic Lactiplantibacillus plantarum MTCC (Microbial Type Culture Collection and Gene Bank) 25432, Lactiplantibacillus plantarum MTCC 25433, and Lactobacillus acidophilus NCIM (National Collection of Industrial Microorganisms) 2902 strains. Results and discussion: The soy milk co-fermented beverage showed highest PAS (1.24 ± 0.02) followed by soy milk beverages fermented with L. plantarum MTCC 25433 (0.753 ± 0.0) when compared to the commercial prebiotic raffinose (1.29 ± 0.01). The findings of this study suggested that the soy milk beverages exhibited potent prebiotic activity, having the ability to support the growth of probiotics, and the potential to raise the content of several bioactive substances. The higher prebiotics activity score showed that the higher the growth rate of probiotics microorganism, the lower the growth of pathogen. For acidic tolerance, all fermented soy milk managed to meet the minimal requirement of 106 viable probiotic cells per milliliter at pH 2 (8.13, 8.26, 8.30, and 8.45 logs CFU/ mL, respectively) and pH 3.5 (8.11, 8.07, 8.39, and 9.01 log CFU/mL, respectively). The survival rate of soy milk LAB isolates on bile for 3  h ranged from 84.64 to 89.60%. The study concluded that lactobacilli could thrive in gastrointestinal tract. The sensory evaluation scores for body and texture, color, flavor, and overall acceptability showed a significant difference (p  <  0.05) between the fermented probiotic soy milk and control samples. Soy milk fermented with a combination of L. plantarum MTCC 25432 & MTCC 25433 demonstrated the highest acceptability with the least amount of beany flavor. The findings of the study suggest soy milk’s potential in plant-based beverage market.
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    Mathematical modeling and parameter analysis of quantum antenna for IoT sensor-based biomedical applications
    (2023-08) Goyal, N; Rana, A; Singh, H; Krishna, R
    In this paper, an equivalent combination of series and parallel R-L-C high-pass filter circuit is derived for a nano (quantum) antenna for the Internet of thing (IoT) based sensors for speedy data or organ image displaying in medical line surgeries. The proposed method utilized the sample frequency behavior of characteristics mode to develop a fundamental building block that superimposes to create the complete response. The resonance frequency, input impedance, and quality factor have been evaluated along with basic and higher-order resonating modes. The relation between quality factor, bandwidth, resonance frequency, and selectivity for higher order, increases the quantum circuits in terms of increased order of a filter, quality factor, and odd and even harmonics factors. Therefore, the basic circuits derivation factor of frequency coefficients are expanded in terms of polynomials and then they are expressed as a simple rational function from which the basic circuit parameters are calculated. In this circuit input impedance of each circuit’s element is complex. The real part of input impedance depends on frequency, depending on the frequency positive or negative value of the resistor, and the imaginary part of impedance modelling an inductor or capacitor due to the value of frequency. At cutoff frequency 511 THz, z11 and VSWR parameters are 34 Ω and 1.11, respectively. The proposed quantum DRA is tested at 5 THz, 10 THz, and 500 THz by calculating the electrical parameters like R, L, C and model performance is quite good as compared to existing ones. The dynamic impedance is dependent on the skin effect and enhances the detailed discussion below. The utilization of optical or quantum DRAs is as optical sensors in biomedical engineering, speedy wireless communication, and optical image solutions. Analyte material has been used for monitoring frequency deviation.